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Cell lines have played a significant role in the recent rapid progress that has been made in understanding the molecular events involved in the functioning of the nervous system. Now that systems for generating new cell lines from defined regions of the nervous system have been developed, and the technology for generating transgenic animals with specific gene deletions is available, neuronal cell lines will provide important tools for defining the molecules and mechanisms involved in gene regulation, cell-cell interactions, and the electrical properties of neurons. This instructive book presents clear practical advice on the production and exploitation of neuronal cell lines in areas ranging from transcriptional regulation to the definition of cell adhesion mechanisms. The techniques described will be useful to researchers in neurobiology as well as to physiologists and anatomists interested in molecular biology. The book also provides insight into the technology of cell line generation and the possibilities afforded by transgenic technology.
- Sales Rank: #7492858 in Books
- Published on: 1992-09-10
- Original language: English
- Dimensions: 9.25" h x .62" w x 6.25" l, .91 pounds
- Binding: Paperback
- 292 pages
Review
'The book is aimed mainly at laboratory workers, is well referenced and contains details of suppliers of specialist items needed in laboratory research.' Aslib Book Guide, Vol. 58, No. 1, January 1993
About the Author
John N. Wood, Head of Neuroimmunology, The Sandoz Institute for Medical Research, London.
Most helpful customer reviews
0 of 0 people found the following review helpful.
Layman's guide to complicated science
By John A. Kadavil
For those just starting in the basics of nerve cell research, this book provides a great tutorial in the art of nerve cell culture and in vitro assays. I found it especially helpful for 32-P labeling. A must have for any scientist, whether a beginner or an expert in neuronal cell lines. Also great for trouble shooting.
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